Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPLISIDSRKHLFYEEYGQ----GIPIIFIHPPGMGRKVFYYQ-RLLSKHFRVIFPDLSGHGDSDHIDQPASISYY--ANEIAQFMDALHIDKAVLFGYSAGGLIAQHIGFTRPDKVSHLILSGAYPAVHN--VIGQK-LHK-LG-MYLL-EKNPGLLMKILAGSHTKDRQLRSILTDHMKKADQAHWHQYYLDSLGYNCIEQLPRLEMPMLFMYGGLRDWTFTNA-GYYRRSCRHAEFFRLEYQGHQLPTKQWKTCNELVTGFVLTHHS 2XUA Chain:A ((6-264)) ---YAAVNGTELHYRIDGERHGNAPWIVLSNSLGTDLSMWAPQVAALSKHFRVLRYDTRGHGHSEAPKGP--YTIEQLTGDVLGLMDTLKIARANFCGLSMGGLTGVALAARHADRIERVALCNTAARIGSPEVWVPRAVKARTEGMHALADAVLPRWFT--ADYMEREPVVLAMIRDVFVHTDKEGYASNCEAIDAADLRPEAPGIKVPALVISGTHDLAATPAQGRELAQAIAGARYVEL-DASHISNIERADAFTKTVVDFLTE---

General information: TITO was launched using: RESULT: Template: 2XUA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1472 1225 0.83 5.00 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 0.83 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.338

(partial model without unconserved sides chains): PDB file : Tito_2XUA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XUA-query.scw PDB file : Tito_Scwrl_2XUA.pdb: