Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFNQVMLVGRLTKDPDLRYTSAGAAVAHVTLAVNRSFKNASG--EIEADYVNCTLWRKTAENTALYCQKGSLVGVSGRIQTRSYENEEGVNVYVTEVLADTVRFMDPKPREKAAD 1SE8 Chain:A ((128-233)) AMNEVLVLGNVTRDPEIRYTPAGDAVLSLSIAVNENYQDRQGQRQEKVHYIDATLWRDLAENMK-ELRKGDPVMIMGRLVNEGWT------RNSTRVEATRVEALAR--------

General information: TITO was launched using: RESULT: Template: 1SE8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 401 -25687 -64.06 -262.11 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -64.06 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.521

(partial model without unconserved sides chains): PDB file : Tito_1SE8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1SE8-query.scw PDB file : Tito_Scwrl_1SE8.pdb: