Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence SVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAED-YYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAE 4FG7 Chain:A ((14-277)) ----EDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIA----------------SMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPG--------TPGYVAPEVLAQ---K--SKAVDCWSIGVIAYILLCGYPPFYDEN-DAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIA--------------------------------------------

General information: TITO was launched using: RESULT: Template: 4FG7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -172592 for 1866 contacts (-92.5/contact) + 2D Compatibility (PS) -26197 + (NN) -16063 + (LL) 4348 1D Compatibility (HY) -26000 + (ID) 5450 Total energy: -241954.0 ( -129.66 by residue) QMean score : 0.439

(partial model without unconserved sides chains): PDB file : Tito_4FG7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FG7-query.scw PDB file : Tito_Scwrl_4FG7.pdb: