Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKFAVIVLPGSNCDIDMYHAVKDELGHEVEYVWHEE--TSL--DGFDGVLIPGGFSYGDYLRCGAIARFANIMPAVKQAAAEGKPVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQNDETLFTASYEKG------ESITIPVAHGEGNFYCDDETLATLKENNQIAFTYGSNINGSVSDIAGVVNEKGNVLGMMPHPERAVDELLGSADGLKLFQSIV-KNWRETHVTTA 3TQI Chain:A ((8-244)) HRILILDFGSQ-YAQLIARRVREI-GVYCELMPCDIDEETIRDFNPHGIILSGGPE------------------APAFIFEIGCPVLGICYGMQTMAYQL---GGKVN------EFGHAQLRVL-NPAFLFDGIEDQVSPQGEPLLDVWMSHGDIVSELP---------PGFEATAC--TDNS---PLAAMADFKRRFFGLQFHPEVTHTP-QG----HRILAHFVIHICQ-------

General information: TITO was launched using: RESULT: Template: 3TQI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1045 -134737 -128.93 -787.93 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -128.93 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.403

(partial model without unconserved sides chains): PDB file : Tito_3TQI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TQI-query.scw PDB file : Tito_Scwrl_3TQI.pdb: