Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLYGVIGNPIGHSMSPDIHNASLKDLGLDGHYHAFKVEENDLEDAVKGIRALGVQGINVTVPHKVSIMDYLDHIDESAKVLGAVNTV-RREGD-KLVGYNTDGEGFVKSLMKVLDKPISELSFLMIGAGGAARAIFT-----------TIVRNTPKKFDICNRTLEKAKRLTEATPSFHNKEVLSIKEAEE-RLEQYDVIIHTTSVGMYPNVDDVPLSLQRAASSAVVCDIVYNPIQTALLKEASQKGLKTLDGVGMFVEQAALSFQLWTGQEPNIEKMRSIVIGKLGGTEC 2GPT Chain:A ((235-518)) --KVYGIIGKPVSHSKSPIVHNQAFKSVDFNGVYVHLLV--DNLVSFLQAYSSSDFAGFSCTIPHKEAALQCCDEVDPLAKSIGAVNTILRRKSDGKLLGYNTDCIGSISAIEDGL-------------------TVVVIGAGGAGKALAYGAKEKGAKVVIANRTYER--ELAEAI----G--ALSLTDLDNY--EDGMVLANTTSMGMQPNVEETPISKDALKHYALVFDAVYTPRITRLLREAEESGAITVSGSEMFVRQAYEQFEIFTGL-PAPKELYWQIMSKYGSRE-

General information: TITO was launched using: RESULT: Template: 2GPT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1462 -16685 -11.41 -68.10 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -11.41 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.498

(partial model without unconserved sides chains): PDB file : Tito_2GPT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2GPT-query.scw PDB file : Tito_Scwrl_2GPT.pdb: