Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIMKMTHLNMKDFNKPNEPFVVFGRMIPAFENGVWTYTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRI--KIRSNWNGYALIE-DIAVAKDYRKKGVGTA-LLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFPTANEIAIFWYYKF 2OB0 Chain:A ((2-155)) ---------------SKGSRIELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVL------EVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEIIETKKNYYKRIEPAD--AHVLQKNL

General information: TITO was launched using: RESULT: Template: 2OB0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 649 -58017 -89.39 -386.78 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -89.39 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.239

(partial model without unconserved sides chains): PDB file : Tito_2OB0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OB0-query.scw PDB file : Tito_Scwrl_2OB0.pdb: