Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGWVAKIFRVGRVVEPAAPLPAAIAEPPAGVRGSLQIRHVDAGSCNGCEVEISGAFGPVYDAERFGARLVASPQHADALLVTGVVTHNMAGPLRKTLEATPR-PRVVIACGDCALNRGVFADAYGVVGAVGEVVPVDVEIAGCPPTPAAIMAALRSVTGK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 4ZM6 Chain:A ((8-858)) NLDKEIGQLLMCGFDGLEPTPGIIDLIENHNLGSIILFSRNIATPKQVQKLTHSLQQIARNAGHKRPLFIAVDQENGVVRRLGDSGTYLPGNMALGALGSSTAARNVAMAISKELLTLGMNWNLAPVLDVNNNPLNPVIGVRSYGQDPELVARMGLAQVEGYQRGKVATSIKHFPGHGDTATDSHLDVPVINKTLEELDKTELVPFKKALEAGGIACPTSVMVGHMLLPHFNKDVVSSIAPEIVRDLLRRRFGYKGVIITDCLEMDAVKETVGTPKGALMALQAGNDMAMISHTLAFQKDAFKVLYSALQEGQLDKDEIRQSLQRVAQLKDQFLNWDDVLQQADLKTMGSEAHATLSKELYDRVPTVVTNRKNTLPIRPAQTDKILFLAAHVPEK--EPFNSFHASLLKRH-------------TNLEYIIYNEET--PDLSQKIQEADWVIIGTANANLYPFQVRMVQQAQKLAKRLVVAAVMNPYDQMCFP-------------QVDTYLVTYEYTPPAHEAAVRLIFGEIETRSRLPISIPNVDDAIAPATFIVDDYRNDDDLDHVTAMWDDIFGKDWPLRKDKINLGLQRAKLQKHKVARDSQGKIVGFVATQIVVVDNKKHGQLMLLMVSPSYQGKGVGTLLHDAALEHFREQGADCIKLGSTYPRFFPGVPDDDAQSRKAQAFFSKKGWRMDDNLVHDLIGDLQDYKVPDKIQARMLKEKIWFGRIKPSETWELYAFQQRNFPHWLSTYQHHVELGDYQDLIVARQDDENGRVIASLILNTTHVSHEYRSDLIWTDDKLFGERSGGMACVGVAQEERGRGIGIGIVAHANWLLKQRGVTKSYVDWVELLDFYSRVGYKTWRSYRLGHF

General information: TITO was launched using: RESULT: Template: 4ZM6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -48771 for 1037 contacts (-47.0/contact) + 2D Compatibility (PS) -13695 + (NN) -1812 + (LL) 1684 1D Compatibility (HY) -3600 + (ID) 1500 Total energy: -67694.0 ( -65.28 by residue) QMean score : 0.167

(partial model without unconserved sides chains): PDB file : Tito_4ZM6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ZM6-query.scw PDB file : Tito_Scwrl_4ZM6.pdb: