Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVANVEPNDGHRAIAAWQDHAEV-SVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYT--DALPEMPEPAIEVEPPVCD-CGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAIVYPAAGLPDLALARGTAVIEVNPEPTPLSGSATISIRESASQALPGLLERLPALLK 2H2H Chain:A ((19-227)) -----LTGAGISTPSGIPDF--------------NVFDIDFFYSHPEEFYRFAKEGIFPMLQAKPNLAHVLLAKLEEKGLIEAVITQNIDRLHQRAGSKKVIELHGNVEEYYCVRCEKKYTVEDVIKKLESSDV----PLCDDCNSLIRPNIVFFGENLPQDALREAIGLSSRASLMIVLGSSLVVYPAAELPLITVRSGGKLVIVNLGETPFDDIATLK---------------------

General information: TITO was launched using: RESULT: Template: 2H2H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -83060 for 1526 contacts (-54.4/contact) + 2D Compatibility (PS) -20947 + (NN) -7170 + (LL) 3216 1D Compatibility (HY) -20000 + (ID) 3750 Total energy: -131711.0 ( -86.31 by residue) QMean score : 0.434

(partial model without unconserved sides chains): PDB file : Tito_2H2H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H2H-query.scw PDB file : Tito_Scwrl_2H2H.pdb: