Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFAT---LRREAPISFWPTIELPGFVAGNGHWALTKYDDVFYASRHPDIFSSYPNITINDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAAVRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQRIFHWTNVILGFGDPDLATDFDEFMQVSADIGAYATALAEDRRVNHHDDLTSSLVE-AEVDGERLSSREIASFFILLVVAGNETTRNAITHGVLALSRYPEQRDRWWSDFDGLAPTAVEEIVRWASPV-VYMRRTLTQDIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGGGAHFCLGANLARREIRVAFDELRRQMPDVVATEEPARLL---SQFIHGIKTLPVTWS 4UMZ Chain:A ((35-425)) ----------------------------LDLGALGQDFAADPYPTYARLRAEGPAHRVRTPE------GNEVWLVVGYDRARAVLADPRFSKDWRNSTTPLTEAE-AALNHNMLESDPPRHTRLRKLVAREFTMRRVELLRPRVQEIVDGLVDAMLAA-PDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVFPDDPAQA------QTAMAEMSGYLSRLIDSKRGQDGEDLLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMYALLSHPDQLAALRADMT-LLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRRDTAGHLAF-GHGIHFCIGAPLARLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRW-

General information: TITO was launched using: RESULT: Template: 4UMZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -194773 for 3084 contacts (-63.2/contact) + 2D Compatibility (PS) -40383 + (NN) -10047 + (LL) 1436 1D Compatibility (HY) -23600 + (ID) 7000 Total energy: -274367.0 ( -88.96 by residue) QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_4UMZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UMZ-query.scw PDB file : Tito_Scwrl_4UMZ.pdb: