Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNK----LFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ-----KAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN 4HGL Chain:A ((5-302)) ----------LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIG--RPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW-IGKQLPTPV----------------------------------

General information: TITO was launched using: RESULT: Template: 4HGL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -124408 for 2277 contacts (-54.6/contact) + 2D Compatibility (PS) -30903 + (NN) -10652 + (LL) 1696 1D Compatibility (HY) -29600 + (ID) 8050 Total energy: -201917.0 ( -88.68 by residue) QMean score : 0.490

(partial model without unconserved sides chains): PDB file : Tito_4HGL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HGL-query.scw PDB file : Tito_Scwrl_4HGL.pdb: