Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFD---DTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 2QHM Chain:A ((9-264)) ------------------------WDLVQTLG----GEVQLAVNRVTEEAVAVKIVDMK-------N--IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVF-------------RYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS--------------------

General information: TITO was launched using: RESULT: Template: 2QHM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -134481 for 1873 contacts (-71.8/contact) + 2D Compatibility (PS) -24972 + (NN) -1172 + (LL) 3440 1D Compatibility (HY) -15200 + (ID) 4100 Total energy: -176485.0 ( -94.23 by residue) QMean score : 0.365

(partial model without unconserved sides chains): PDB file : Tito_2QHM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QHM-query.scw PDB file : Tito_Scwrl_2QHM.pdb: