Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSFSSLQDKGMKNSEFLKGEVSFEQKAKILLEALSSIPNFVGETFVIKCGGITISDETLFNTFVHNVVLLKQLGINPVIVHDGEYEIDSVLKILGINSKFVNDIRLTDKDTMRIIEMVLCGSINKKIVQHINSAGGSAIGLCGKDGNLIKAEKISTTLRENGSNNVEKILDMGFIGIPTEINPDILFFIEESDFIPVIAPIGHGKNGETYHIDADGAAGAIAVAVSASKMIIFSDVCEEMDKIDG-----RKISVKNLNASINCGKIKGERFVEKLTACAKMVEECAGIAHIVNGRIPNIMIDL-FTESNSSVSIVNDL 2RD5 Chain:A ((18-298)) -----------------------DYRVEILSESLPFIQKFRGKTIVVKYGGAAMTSPELKSSVVSDLVLLACVGLRPILVHGGGPDINRYLKQLNIPAEFRDGLRVTDATTMEIVSMVLVGKVNKNLVSLINAAGATAVGLSGHDGRLLTARPVP------------NSAQLGFVGEVARVDPSVLRPLVDYGYIPVIASVAADDSGQAYNINADTVAGELAAALGAEKLILLTDVAGILENKEDPSSLIKEIDIKGVKKMIEDGKVAG-GMIPKVKCCIRSLAQGVKTASIIDGRRQHSLLHEIMSDEGAGTMITG--

General information: TITO was launched using: RESULT: Template: 2RD5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -213575 for 2287 contacts (-93.4/contact) + 2D Compatibility (PS) -29790 + (NN) -10572 + (LL) 1780 1D Compatibility (HY) -23600 + (ID) 4500 Total energy: -280257.0 ( -122.54 by residue) QMean score : 0.587

(partial model without unconserved sides chains): PDB file : Tito_2RD5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2RD5-query.scw PDB file : Tito_Scwrl_2RD5.pdb: