Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKFAVIVLPGSNCDIDMYHAVKDELGHEVEYVWHEET----SLDGFDGVLIPGGFSYGDYLRCGAIARFANIMPAVKQAAAEGKPVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQNDETLFTASYEKGESITIPVAHGEGNFYCDDETLATLKENNQIAFTYGSNINGSVSDIAGVVNEKGNVLGMMPHPERAVDELLGSADGLKLFQSIV-KNWRETHVTTA 2VXO Chain:A ((31-227)) -AVVILDAG--YG-KVIDRRVREL-FVQSEIFPLETPAFAIKEQGFRAIIISGGP----------APWF------DPAIFTIGKPVLGICYGMQMMNKVF---GGTVHK--------VFNISVD-NTCSLFRGLQK--EEVVLLTHGDSVDKVA---------DGFKVVAR--SGN----IVAGIANESKKLYGAQFHPEVGLTE-NG----KVILKNFLYDIAGC------

General information: TITO was launched using: RESULT: Template: 2VXO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 969 -109382 -112.88 -658.93 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -112.88 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.523

(partial model without unconserved sides chains): PDB file : Tito_2VXO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VXO-query.scw PDB file : Tito_Scwrl_2VXO.pdb: