Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHRLLLLMMLTALGVAGCGQKKPPDPPNRVPEKKVVETSAFGHHVQLVNREGKAVGFIEIKESD-DEGLDIHISANSLRPGASLGFHIYEKGSCVRPDFESAGGPFNPLNKEHGFNNPMGHHAGDLPNLEVGADGKVDVIMNAPDTSLKKGSKLNILDEDGSAFIIHEQADDYL------TNPSGNSGARIVCGALLGNNEKQ 4A7U Chain:A ((2-152)) ----------------------------------------TKAVCVLKG-DGPVQGIINFEQKESNGPVKVWGSIKGLTEGL-HGFHVHEFGDNTAG-CTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSG-----DHCITGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIA----

General information: TITO was launched using: RESULT: Template: 4A7U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 817 7994 9.78 55.51 target 2D structure prediction score : 0.80 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 9.78 2D Compatibility (Sec. Struct. Predict.) : 0.80 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.469

(partial model without unconserved sides chains): PDB file : Tito_4A7U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4A7U-query.scw PDB file : Tito_Scwrl_4A7U.pdb: