Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFIDTHCHLDHKDYENDLDEVLKESLEKGVTQCVIPGADMKDLNRAVGISEKFEGVFFAIGAHPYDVESFDEGLFEKFV---SHQKCVAIGECGLDYYRLPELSERENYKS--KQKEIFTKQIEFSIQHNKPLIIHIREASFDSLNLLKSYPKAF--GVLHCFNA--DSMLLELSDRFYYGI-GGVSTFKNAKRLVEILPKIPKNRLLLETDSPY-----LTPHPFRGTRNSPTYIPLIAQKIAEIIHIETEELASLSTHNAQTLFNFP 4PE8 Chain:A ((1-258)) MF-DIGVNLTSSQFAKDRDDVVACAFDAGVNGLLITGTNLRESQQAQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNR--------NFSTPEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREEMQACVAHGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKP-SSRRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIA

General information: TITO was launched using: RESULT: Template: 4PE8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -154256 for 2088 contacts (-73.9/contact) + 2D Compatibility (PS) -26276 + (NN) -18091 + (LL) 932 1D Compatibility (HY) -18000 + (ID) 4000 Total energy: -219691.0 ( -105.22 by residue) QMean score : 0.572

(partial model without unconserved sides chains): PDB file : Tito_4PE8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4PE8-query.scw PDB file : Tito_Scwrl_4PE8.pdb: