Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLDQIDLNIIEELKKDSRLSMRELGRKIKLSPPSVTERVRQLESFGIIKQYTLEVDQKKLGLPVSCIVEAT-VKNADYERFKSYIQTLPNIEFCYRIAGAACYMLKINAESLEAVEDFINKTSPYAQTVTHVIFSEIDTKNGRG 2VBX Chain:B ((5-124)) --LDDIDRILVRELAADGRATLSELATRAGLSVSAVQSRVRRLESRGVVQGYSARINPEAVGHLLSAFVAITPLDPSQPDDAPARLEHIEEVESCYSVAGEESYVLLVRVASARALEDLLQR-----------------------

General information: TITO was launched using: RESULT: Template: 2VBX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 329 -67625 -205.55 -568.28 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : -205.55 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.569

(partial model without unconserved sides chains): PDB file : Tito_2VBX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VBX-query.scw PDB file : Tito_Scwrl_2VBX.pdb: