Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTLTVKDIKDRLQEVKDAQDPFIAQCENDPRKSVQTLVEQWLKKQAKEKALKEQWVNMTSYERLARNKGFRLIAGVDEVGRGPLAGPVVASAVILPEE----CEILGLTDSKKLSEKKREEYYELIMKEALAVGIGIVEATVIDE----INIYEASKMAMVKAIQDLSDTPDYLLVDAMTL-PLDTA---------QASII---KGDAKSVSIAAGACIAKVTRDRMMSAYAETYPMYGFEKNKGYGTKEHLEALAAYGPTELHRKTFAPVQSFR 1UAX Chain:A ((3-181)) -------------------------------------------------------------------------VAGVDEAGRGPVIGPLVIGVAVIDEKNIERLRDIGVKDSKQLTPGQREKLFSKLIDILDDYYVLLVTPKEIDERHHSMNELEAEK--FVVALNSLRIKPQKIYVDSADVDPKRFASLIKAGLKYEATVIAEHKADAKYEIVSAASIIAKVTRDREIEKLKQKYGEFGSGYPSDPRTKEWLE----------------------

General information: TITO was launched using: RESULT: Template: 1UAX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 750 -74958 -99.94 -474.42 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -99.94 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.363

(partial model without unconserved sides chains): PDB file : Tito_1UAX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1UAX-query.scw PDB file : Tito_Scwrl_1UAX.pdb: