Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIDYVSDLHINHWIPWNVNQIKWEKRTREIVNRLIS-NGNGEVLVIAGDFTEWNQ--QTLWVLDEAA----KQYEKVYFTYGNHDLYLLSKSQKRKYSDSLGRLNDLIQKAADMKNVTPLIKTTETYKGKVFAGDVMWYLPKGIEGWDFFKGVSNDSNYIWLNGYNKVDGVRAMWKESMDW-YETLE--NTQVDVFVSHVPPVHNPYSPF-E--P--NTCYMVDVPFINAKHWVCGHDHLQAEFDKDGTSFHMN-CIGYPYDYDNYPSVNVIPGEEVDSYKTFELKTFEI 3IB7 Chain:A ((26-241)) YVLLHISDTHLIGGDRRLYGAVDADDRLGELLEQLNQSGLRPDAIVFTGDLADKGEPAAYRKLRGLVEPFAAQLGAELVWVMGNHDDRAELRKF----------LLDEAP---SM-A---PLDRVCMIDGLRIIVLDTSVPGHH-------------------HG--------EIRASQLGWLAEELATPAPDGTILALHHPPIPSVLDMAVTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCY-------------------------------

General information: TITO was launched using: RESULT: Template: 3IB7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 988 -16667 -16.87 -83.34 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -16.87 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.364

(partial model without unconserved sides chains): PDB file : Tito_3IB7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IB7-query.scw PDB file : Tito_Scwrl_3IB7.pdb: