Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSHDWTDNRKNLMLFAGRAHPELAEQVAKELDVHVTSQDAREFANGEIFVRFHESVRGCDAFVLQSCPAPVNRWLMEQLIMIDALKRGSAKRITAVMPFYPYARQDKKHRGREPISARLIADLLKTAGADRIVTVDLHTDQIQGFFDGPVDHMRGQNLLTGYIRDNYPDG-NMVVVSPDSGRVRIAEKWADALGGVPLAFIHKTRDPRVPNQVVSNRVVGDVAGRTCVLIDDMIDTGGTIAGAVALLHNDGAGDVIIAATHGVLSDPAAQRLASCGAREVIVTNTLPIGED--KRFPQLTVLSIAPLLASTIRAVFENGSVTGLFDGDA 2HCR Chain:A ((3-313)) ----------NIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRL-NVDFALIHKER--------DRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIP-QEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLF----

General information: TITO was launched using: RESULT: Template: 2HCR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -282851 for 2583 contacts (-109.5/contact) + 2D Compatibility (PS) -34485 + (NN) -26982 + (LL) 384 1D Compatibility (HY) -27200 + (ID) 6700 Total energy: -377834.0 ( -146.28 by residue) QMean score : 0.614

(partial model without unconserved sides chains): PDB file : Tito_2HCR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HCR-query.scw PDB file : Tito_Scwrl_2HCR.pdb: