Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYK--------GQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRT--PSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG 2Y00 Chain:A ((15-285)) -------SLLMALVVLLIVAGNVLV-IAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPGCCDF--VTNRAYAIASSIISFYIPLLIMIFV---ALRVYREAKEQ----------------SRVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNW-LGYANSAMNPIIYCRSPDFRKAFKRLLA-----------------------------------------

General information: TITO was launched using: RESULT: Template: 2Y00.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -232966 for 1831 contacts (-127.2/contact) + 2D Compatibility (PS) -25435 + (NN) -10961 + (LL) 5760 1D Compatibility (HY) -28000 + (ID) 3650 Total energy: -295252.0 ( -161.25 by residue) QMean score : 0.400

(partial model without unconserved sides chains): PDB file : Tito_2Y00.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y00-query.scw PDB file : Tito_Scwrl_2Y00.pdb: