Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLMNYSSATEFYLLGFPGSEELHHILFAIFFFFYLVTLMGNTVIIMIVCVDKRLQSPMYFFLGHLSALEILVTTIIVPVMLWGLLLPGMQTIYLSAC----VVQLFLYLAVGTTEFALLGAMAVDRYVAVCNPLRYNIIMNRHTCNFVVLVSWVFGFLFQIWPVYVMFQLTYCKSNVVNNFFCDRGQLLKLSCNNTLFTEFILFLMAVFVLFGSLIPTIVSNAYIISTILKIPSSSGRRKSFSTCASHFTCVVIGYGSCLFLYVKPKQTQAADYNWVVSLMVSVVTPFLNPFIFTLRNDKVIEALRDGVKRCCQLFRN 4UHR Chain:A ((18-164)) ----------------------------------VLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLAIPFAI------AISTGFCAACHGCLFIACFVLVLTASSIFSLL-AIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKA---GCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREF

General information: TITO was launched using: RESULT: Template: 4UHR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -125190 for 917 contacts (-136.5/contact) + 2D Compatibility (PS) -13833 + (NN) -3359 + (LL) 3168 1D Compatibility (HY) -14800 + (ID) 1850 Total energy: -155864.0 ( -169.97 by residue) QMean score : 0.150

(partial model without unconserved sides chains): PDB file : Tito_4UHR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UHR-query.scw PDB file : Tito_Scwrl_4UHR.pdb: