Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIE--DNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS 2XK3 Chain:A ((7-262)) --------------------------------DYEVLYTIGT----RCQKIRRKSDGKILVWKELDYGSMTEAEKQM-LVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRS---RDLKPANVFLDGKQNVKLGDFG---------------VGTPYYMSPEQMNR---NEKSDIWSLGCLLYELCALMPPFTA--FSQKELAGKIREGKFRRIPY-RYSDELNEIITRMLNLKDYHRPSVEEILENPLILEHHHHHH

General information: TITO was launched using: RESULT: Template: 2XK3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -131923 for 1616 contacts (-81.6/contact) + 2D Compatibility (PS) -24429 + (NN) -16899 + (LL) 2376 1D Compatibility (HY) -21600 + (ID) 4350 Total energy: -196825.0 ( -121.80 by residue) QMean score : 0.553

(partial model without unconserved sides chains): PDB file : Tito_2XK3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XK3-query.scw PDB file : Tito_Scwrl_2XK3.pdb: