Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---AISCGQVSSALSPCISYARG---------NGAKPPVACCSGVKRLAGAAQSTADKQA------------------ACRCLKSLATSIKGINMGKVSGVPGKCGVSVPFPISMSTDCNKVH- 4HR1 Chain:A ((3-120)) FNGAQTVIQKISWLRTAIAFLKGYMETTGATKKELEQVEKLKERVDEIATAVNWDVYAQYARGDFNLLSDDEYKEIQKALLVLEDIKEQII-VEMLRVGLAQGQMG-----TLKISDYLDSLDS

General information: TITO was launched using: RESULT: Template: 4HR1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -38080 for 544 contacts (-70.0/contact) + 2D Compatibility (PS) -8723 + (NN) 1679 + (LL) 176 1D Compatibility (HY) -5600 + (ID) 900 Total energy: -51448.0 ( -94.57 by residue) QMean score : 0.340

(partial model without unconserved sides chains): PDB file : Tito_4HR1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HR1-query.scw PDB file : Tito_Scwrl_4HR1.pdb: