Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLTPKELDKLMLHYAGELARKRKEKGIKLNYVEAVALISAHIMEEARAGKKTAAELMQEGRTLLKPDDVMDGVASMIHEVGIEAMFPDGTKLVTVHTPIE-ANGKL----------------------VPGELFLKNEDITINEGKKAVSVKVKNVGDRPVQIGSHFHFFEVNRCLDFDREKTFGKRLDIASGTAVRFEPGEEKSVELIDIGGNRRIFGFNALVDRQADNESKKIALHRAKERGFHGAKSDDNYVKTIKE 4GOA Chain:A ((1-247)) MKLSPREVEKLGLHNAGYLAQKRLARGVRLNYTEAVALIASQIMEYARDGEKTVAQLMCLGQHLLGRRQVLPAVPHLLNAVQVEATFPDGTKLVTVHDPISRENGELQEALFGSLLPVPSLDKFAEDNRIPGEILCEDECLTLNIGRKAVILKVTSKGDRPIQVGSHYHFIEVNPYLTFDRRKAYGMRLNIAAGTAVRFEPGDCKSVTLVSIEGNKVIRGGNAIADGPVNETNLEAAMHAVRSKGFGHEEEKDASEGFTKE

General information: TITO was launched using: RESULT: Template: 4GOA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -61078 for 1523 contacts (-40.1/contact) + 2D Compatibility (PS) -24095 + (NN) -12112 + (LL) 0 1D Compatibility (HY) -20800 + (ID) 5900 Total energy: -123985.0 ( -81.41 by residue) QMean score : 0.507

(partial model without unconserved sides chains): PDB file : Tito_4GOA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4GOA-query.scw PDB file : Tito_Scwrl_4GOA.pdb: