Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MILEVKDLKTYFFTDKGVNKAVDGVSFGLKKSQTLCIVGESGSGKSITSLSILGLIE--KPGKIVGGSIQFLGQDLLQLKEKQMQKEIRGKKIGMIFQEPMTSLNPSYTVGFQINEVLKIHHPSLNKKERLERVVYEL-ERVGIPHAGDKYHEYPFNLSGGQRQRVMIAMAMVCEPEILIADEPTTALDVTIQAQILELMKELQQKKGTSILFITHDLGVVAQIADEVVVMYKGHVVEQASAKELFADPRHPYTKALLNAIPKPGKEYRKKRLETVDENVDYLSFQKELR 4U00 Chain:A ((4-241)) -IIRIRNLHKWF----GPLHVLKGIHLEVAPGEKLVIIGPSGSGKS-TLIRTINRLEDFQEGEVV--------VDGLSVKDDRALREIR-REVGMVFQQ--FNLFPHMTV--LENVTLAPMRVRRWPREKAEKKALELLERVGIL---DQARKYPAQLSGGQQQRVAIARALAMEPKIMLFDEPTSALDPEMVGEVLDVMRDLAQ-GGMTMVVVTHEMGFAREVADRVVFMDGGQIVEEGRPEEIFTRPKEERTRSFLQRVLH---------------------------

General information: TITO was launched using: RESULT: Template: 4U00.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -123399 for 1935 contacts (-63.8/contact) + 2D Compatibility (PS) -25974 + (NN) -14034 + (LL) 2056 1D Compatibility (HY) -18800 + (ID) 4400 Total energy: -184551.0 ( -95.38 by residue) QMean score : 0.484

(partial model without unconserved sides chains): PDB file : Tito_4U00.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4U00-query.scw PDB file : Tito_Scwrl_4U00.pdb: