Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNPIQHILDTYPLIVLDGAMATELERKGCNLNDSLWSAKILMEEPELIKQVHTDYFAAGADCAITASYQSTFEGFAARGLSEAEARRLIELSVSIAAEARDEFWSLEENRLNRPKPIIAASIGPYGAYLADGSEYRGNYAISEDELIEFHRPRMKALIEAGADVLACETIPCLTEAKAIVRLLKEFPETYAWISFSAKD--GLHISDGTPAADCASWLDEHRQIAALGINCT--PLQHIPSLIEELKKNTSKPIIVYPNSGEQYDPETKTWNGAACAESYGASARTWHEKGARLIGGCCRTKPENIQEIAAWARSLKTT 1Q7Q Chain:A ((15-281)) ------------VLLLDGAYGTEFMKYGY---DDL-PEELNIKAPDVVLKVHRSYIESGSDVILTNTFGATRMKLRKHGL-EDKLDPIVRNAVRIARRAAGE-------------KLVFGDIGPTGEL-----PYPLGSTLFE-EFYENFRETVEIMVEEGVDGIIFETFSDILELKAAVLAAREVSRDVFLIAHMTFDEKGRSLT-GTDPANFAITFDE-LDIDALGINCSLGPEEILP-IFQELSQYTDKFLVVEPNAGKPIVENGKTVY-PLKPHDFAVHIDSYYELGVNIFGGCCGTTPEHVK------------

General information: TITO was launched using: RESULT: Template: 1Q7Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1562 -139254 -89.15 -529.48 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -89.15 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.472

(partial model without unconserved sides chains): PDB file : Tito_1Q7Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q7Q-query.scw PDB file : Tito_Scwrl_1Q7Q.pdb: