Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKMQNLLAIANEVKEKHANFSISEVNDHCVRLAVFTGEYDWHHHPDSDELFIVLEGELLI------DFKDK-ETAVLKANDSLLIPKGTVHRTRSYVRTVNLCVEHKQAETVIIEEQPC 2ET7 Chain:A ((83-137)) -------------------------------------GTNPPHIHPRATEIGMVMKGELLVGILGSLDSGNKLYSRVVRAGETFVIPRGLMH----------------------------

General information: TITO was launched using: RESULT: Template: 2ET7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 119 -11512 -96.74 -239.82 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -96.74 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.697

(partial model without unconserved sides chains): PDB file : Tito_2ET7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ET7-query.scw PDB file : Tito_Scwrl_2ET7.pdb: