Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNPMIEFCVS--------NLA--HGSQEARAILEKD--------PNLDVLEYGCLSYCGTCMESLFALVN--GEVVMGETPAELVENIYTFIEENPMF 1M2D Chain:A ((3-92)) -FKHVFVCVQDRPPGHPQGSCAQRGSREVFQAFMEKIQTDPQLFMTTVITPTGCMNASM---MGPVVVVYPDGVWYGQVKPEDVDEIVEKHLKG----

General information: TITO was launched using: RESULT: Template: 1M2D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 250 -10757 -43.03 -153.66 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -43.03 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.488

(partial model without unconserved sides chains): PDB file : Tito_1M2D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1M2D-query.scw PDB file : Tito_Scwrl_1M2D.pdb: