Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVTKILKAPDGSPSDVERIKKESDYLRGTLKEVMLDRISAGIPDDDNRLMKHHGSYLQDDRDLRNERQKQKLEPAYQFMLRVRMPGGVSTPEQWLVMDDLSQKYGNGTLKLTTRETFQMHGILKWNMKKTIQTIHSALLDTIAACGDVNRNVMCASNPYQSEIHSEVYEWSKKLSDDLLPRTRAYHEIWLDEERVAGTPEEEVEPMYGPLYLPRKFKIGIAVPPSNDIDVFSQDLGFIAIVEDGKLIGFNVAIGGGMGMTHGDTATYPQLAKVIGFCRP-EQMYDVAEKTITIQRDYGNRSVRKNARFKYTVDRLGLENVKEELENRLGWS--LEEAKPYHFDHNGDRYGWVEGIEDKWHFTLFVE-GGRITDYDDYKLMTGLREI-AKVHTGEFRLTANQNLMIANVSSDKKEEISALIEQYGLTDGKHYSALRRSSMACVALPTCGLAMAE----AERYLPTLLDKIEEIIDENGLRDQEITIRMTGCPNGCARHALGEIGFIGK--------APGKYNMYLGA--AFDGSRLSKMYRENIGEADILSELRILLSRYAKEREEGEHFGDFVIRAGIIKATTDGTNFHD 1ZJ8 Chain:A ((99-560)) ----------------------------------------------------------------------KLEAKY-FMMRVRCDGGALSAAALRTLGQISTEFARDTADISDRQNVQYHWIEVENVPEIWRRLDDVGLQTTEACGDCPRVVL--GSPLAGESLDEV-----------LDPTWAIEEI---VRRYIGKPDFA--------DLPRKYK--TAISGLQDVAHEINDVAFIGVNHPEHGPGLDLWVGGGL-------STNPMLAQRVGAWVPLGEVPEVWAAVTSVFRDYGYRRLRAKARLKFLIKDWGIAKFREVLETEYLKRPLIDGPAPEPVKHPIDHVG-VQRLKNGLNAVGVAPIAGRVSG----TILTAVADLMARAGSDRIRFTPYQKLVILDIPDALLDDLIAGLDALGLQ--SRPSHWRRNLMACSGIEFCKLSFAETRVRAQHLVPELERRLEDI---NSQLDVPITVNINGCPNSCARIQIADIGFKGQMIDDGHGGSVEGFQVHLGGHLGLDAGFGRKLRQHKVTSDELGDYIDRVVRNFVKHRSEGERFAQWVIRA--------------

General information: TITO was launched using: RESULT: Template: 1ZJ8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2667 6427 2.41 14.51 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 2.41 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.390

(partial model without unconserved sides chains): PDB file : Tito_1ZJ8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ZJ8-query.scw PDB file : Tito_Scwrl_1ZJ8.pdb: