Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKVLYITAHPHDEATSYSMATGKAFIESYKEANPNDEVVHIDLYKENIPHIDADVFSGWGKLQSGTGFEELSESEKAKVGRLGELSDQFASADKYVFVTPLWNFSFPPVMKAYLDSVAVAGKSFKYTEQGPVGLLTDKKAIHIQARGGYYSEGPAAEMEMGHRYIGIMMNFFGVPSFDGIFVEGHNAEPDKAQQIKEDAIARAKEAGKTF 3P0R Chain:A ((6-211)) --KVLFVKANNRPAEQAVSVKLYEAFLASYKEAHPNDTVVELDLYKEELPYVGVDMING--TFKAGKGFD-LTEEEAKAVAVADKYLNQFLEADKVVFGFPLWNLTIPAVLHTYIDYLNRAGKTFKYTPEGPVGLIGDKKIALLNARGGVYSEGPAAEVEMAVKYVASMMGFFGATNMETVVIEGHNQFPDKAEEIITAGLEEAAKVANKF

General information: TITO was launched using: RESULT: Template: 3P0R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 991 -102242 -103.17 -496.32 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -103.17 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.553

(partial model without unconserved sides chains): PDB file : Tito_3P0R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P0R-query.scw PDB file : Tito_Scwrl_3P0R.pdb: