Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTLRTLCVLMILSGVIFFGLKIDAKDIDIPFLNSLKKVVSDSDTDSAANSKKELKGSAKPLDVILYNQMDAPRLYNGCEVTSLAMVLNYAGYDVTKNTLANQVATVPLTYSSGLKGDPNDGFVGDMAN--GPGLGVYHRPIYQLAKTY-AGDKVSDLTGKSISAVYQQLEKGNPVWVITTANFTPV--DNMQTWKTPNGTIEITYSEHSVAVTGYDDKYVYLNDPYGYK-NRKTDRTSFEKAWKQMGSQAVVIQK 3ERV Chain:A ((29-224)) -------------------------------------------------------DEKVILSNVPFIQQL--PELDRGCEVTSLAMMLQYAGITVDKMKLANEIKKVDFM-NDGVRGNPNEGFVGNIYTFSESGYGVYHGPLFQLAKKYLPN-KAVDLTGKSIEELYKSVKAGQPVVIITNATFAPLDEDEFTTWETNNGDVSITYNEHCVVLIGYDQESVYIRDPLKDSLDVKVPREKFEQAWVQMGSQAISYV-

General information: TITO was launched using: RESULT: Template: 3ERV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 974 5807 5.96 30.56 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 5.96 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.601

(partial model without unconserved sides chains): PDB file : Tito_3ERV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ERV-query.scw PDB file : Tito_Scwrl_3ERV.pdb: