Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKYEVMYIIRPNIDEESKKAVIERFNNVLTSNGAEITGTKDWGKRRLAYEINDFRDGFYQIVNVQSDAAAVQ-EFDRLAKISDDIIR--HIVVKEEE 2J5A Chain:A ((7-104)) LRYYETVFAVKPTLSEEEMKKKFEQVKEFIKQKGGEILYEEDWGMRQLAYPIQKFNNARYFLVQFKTENPQLPNELDFQLKIDEDVIRWLNIQIKESE

General information: TITO was launched using: RESULT: Template: 2J5A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 385 -22552 -58.58 -237.38 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -58.58 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.617

(partial model without unconserved sides chains): PDB file : Tito_2J5A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2J5A-query.scw PDB file : Tito_Scwrl_2J5A.pdb: