Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPINSFENYPMSWKPSIDKAEKPIYKALAGQLEQDILNGVLLPGTKLPPQRELADYLDLNVSTISKAFKVCELKGLLSATVGSGTFVSYDALSNAYLLEDTKPTHLIEMGAILPDHASYEPLLYQLKNMVHEEDYEKWFSYGRAGESLWQKDAAVKLIQR-GGFETSVDHILFANGGQNAIAATLASLCKPGDRIGVDHHTYPGLKTVASLLSVQIVPIKSEN-------------DEMSPESLEYACKNENIKGLYLIPDYHNPTTSFMSVENRRMVADIVKKYNLFVIEDASYHLLNKNP-LPALASFA---PQQVIHIASLSKSLA-PGLRLAYVAV-PRQYKEPISKALYNLNITVSPLLAELTARTIVSNQFEVLIESHREQTIRRNQLVNRYVAGY--TCLGVETGIFRWLLLPGKM---------------SGAEFEELAA-RLGVQVYAAERFVVGNS--CPERAVRVSVCAPKTLEELEQGLMILRRLLDDLT 3B46 Chain:A ((18-443)) -------------------------------------------------------------PKVV-------ANKYFTSNTAKDVWSLTNEAAAKAANN--QGRELINLGQGFFSYSPPQFAIKEAQKALDI---PMVNQYSPTRGRPSLINSLIKLYSPIYNTELKAENVTVTTGANEGILSCLMGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYVPINPPKELDQRNTRGEEWTIDFEQFEKAIT-SKTKAVIIN-TPHNPIGKVFTREELTTLGNICVKHNVVIISDEVYEHLYFTDSFTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLNAELLSYAAKAHTRICFASPSPLQEACANSINDALKIGYFEKMRQEYINKFKIFTSIFDELGLPYTAPEGTYFVLVDFSKVKIPEDYPYPEEILNKGKDFRISHWLINELGVVAIPPTEFYIKEHEKAAENLLRFAVCK--DDAYLENAVERLKLLKDY--

General information: TITO was launched using: RESULT: Template: 3B46.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2159 -229736 -106.41 -599.83 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -106.41 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.438

(partial model without unconserved sides chains): PDB file : Tito_3B46.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3B46-query.scw PDB file : Tito_Scwrl_3B46.pdb: