Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQGLLTSGRKPSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQR-ERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTF-CGTPEYLAPEVLRKE-----PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQP--LQIPGG---RTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAPEDDDILDC 3QFV Chain:B ((70-407)) ----------------------------------------------------------------------------------------QLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLV-NGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICS-RERRLGQNG-IEDFKKHAFFEGLNWENI--RNLEAPYIPDVSSPSDTSNFD--------------------GFSGLHLPFIGFTFTTESCFSDRG

General information: TITO was launched using: RESULT: Template: 3QFV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -175666 for 2504 contacts (-70.2/contact) + 2D Compatibility (PS) -33299 + (NN) -21766 + (LL) 1252 1D Compatibility (HY) -30800 + (ID) 5850 Total energy: -266129.0 ( -106.28 by residue) QMean score : 0.491

(partial model without unconserved sides chains): PDB file : Tito_3QFV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QFV-query.scw PDB file : Tito_Scwrl_3QFV.pdb: