Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGQKIAVVGATGRVGHEVLSILAEFQDEGKISIDSVITFASKKSKGKKVSFGNEELTVLCLENYDFADIDIAIFCAGYHVSEKYVPIATEAGCIVIDNSSYFRMKEGVPLIIPEINKEKIMEYKNHNIISNPNCTIIQMLLVLHLLYQKAKIKRIVASTYQSTSGAGKAAMDELYNQTKKIFTNEAKKPEIFPKQIAFNCIPHIGEFMEDGSTKEEWKMQEETKKILEA-DIKVTATCVRVPVFIGHAIAVNVEFYQHITEEQAREMLSEVEDTGILVYDRRKDGKYITQI-DVVQENAVYVSRIRKDNTVEHGLNMWIVADNLRKGAALNIVQILEILTREHLSIKCI 2R00 Chain:A ((2-336)) QQFNVAIFGATGAVGETMLEVLQERE----FPVDELFLLASERSEGKTYRFNGKTVRVQNVEEFDWSQVHIALFSAGGELSAKWAPIAAEAGVVVIDNTSHFRYDYDIPLVVPEVNPEAIAEFRNRNIIANPNCSTIQMLVALKPIYDAVGIERINVTTYQSVSGAGKAGID-----------------------------PQIDQFMDNGYTKEEMKMVWETQKIFNDPSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQT--DGIELFRGA---DFPTQVRDAGGKDHVLVGRVRNDISHHSGINLWVVADNVRKGAATNAVQIAELLVRDYF-----

General information: TITO was launched using: RESULT: Template: 2R00.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -244956 for 2589 contacts (-94.6/contact) + 2D Compatibility (PS) -33285 + (NN) -11174 + (LL) 2544 1D Compatibility (HY) -27600 + (ID) 7100 Total energy: -321571.0 ( -124.21 by residue) QMean score : 0.584

(partial model without unconserved sides chains): PDB file : Tito_2R00.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2R00-query.scw PDB file : Tito_Scwrl_2R00.pdb: