Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKQEYKQLPKRAEVHSATEQFKDTIKTSLGLDLFKGLGLTIKEFFSPSVTIHYPMEQLPLSPRYRAVHHLQRLLDSGSERCIGCGLCEKICTSNCIRIITHKGED-----------------NRKKIDSYTINLGRCIYCGLCAEVCPE--LAIVMGNRFENASTQRSQYGSKSEFLTSEQDAKNCSHAEFLGFGAVSPNYNERMQATPLDYVQEPSKEESKEESPTSPESHKGDENV 2C42 Chain:A ((681-767)) --------------------------------------------------------------------------PQWVPENCIQCNQCAFVCPHSAILPVLAKEEELVGAPANFTALEAKGKELKGYKFRIQINTLDCMGCGNCADICPPKEKALVMQPLDTQRDAQVPNLEYAARIPVKSEVLPRDSLKGSQFQEPLMEFSGACSGCGETPYVRVITQLFGERMFIANATGCSSIWGA

General information: TITO was launched using: RESULT: Template: 2C42.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -51899 for 417 contacts (-124.5/contact) + 2D Compatibility (PS) -7405 + (NN) -3823 + (LL) 5640 1D Compatibility (HY) -3600 + (ID) 1050 Total energy: -62137.0 ( -149.01 by residue) QMean score : 0.354

(partial model without unconserved sides chains): PDB file : Tito_2C42.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2C42-query.scw PDB file : Tito_Scwrl_2C42.pdb: