Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKMQNLLAIANEVKEKHANFSISEVNDHCVRLAVF--TGEYDWHHHPDS-DELFIVLEGELLIDFKDKETAVLKANDSLLIPKGTVHRTRSYVRTVNLCVEHKQAETVIIEEQPC 1V70 Chain:A ((1-91)) -MEIKDLKRLARYNPEKMAKIPVFQSERMLYDLYALLPGQAQKVHVH-EGSDKVYYALEGEVVVRVG-EEEALLAPGMAAFAPAGAPHGVRNES----------------------

General information: TITO was launched using: RESULT: Template: 1V70.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 331 -26263 -79.34 -298.44 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -79.34 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.336

(partial model without unconserved sides chains): PDB file : Tito_1V70.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V70-query.scw PDB file : Tito_Scwrl_1V70.pdb: