Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSHSQEKIALITGASSQGDIGTAICRKLASQGIHIFFTHWNSDTAWIEEFQQEILRMGVRCEAMKIDLSDAHAAFTIHEKISDKLGYPSILINNAAHSASDNYVSLDAKSLDEHYAVNMRSNFLLCVEFARRFKKSNLISGRIINMTSGQDLGPL--PGELAYAATKGAISAFTRSLSQELAPLGITVNAVNPGPTDSTWMTDEI----RNFLSPKFPMGRIGTPDDAARMIAFLASDEAEWITGQIIHSEGGFIRG 4BO6 Chain:C ((26-266)) ----QGKVALVTGASR--GIGQAIALELGRLGAVVIGTATSASGA--EKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRD---------EWFDVVNTNLNSLYRLSKAVLRGMTKARW--GRIINI--G---GAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFID-TDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGM---

General information: TITO was launched using: RESULT: Template: 4BO6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1205 -141079 -117.08 -632.64 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain C : 0.79 3D Compatibility (PKB) : -117.08 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.602

(partial model without unconserved sides chains): PDB file : Tito_4BO6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BO6-query.scw PDB file : Tito_Scwrl_4BO6.pdb: