Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLNLQGKTALVTGSTSGIGKAIASSLAEEGAAVIINGRREEKVNQTIDELKTQHAEAVLYPAAFDLGTEEGCNELF----QAYPEVDILVNNLGIFEPAEYFDIPDDEWFRFFEVNIMSGVRLTRRYLHNMIEKKEGRVIFIASEAAIMPSQEMAHYSATKTMQLSISRSLAELATGTNVTVNTVMPGSTLTEGVETMLNSLYPGENLTVQEAEARFMKENRPTSIIQRLIRPEEIAHFVTFLSSPLSSAINGAALRADGGLVRSVF 2Q2Q Chain:C ((2-253)) ----LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPA--PALAEIARHGVKAVHHPA--DLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTRLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAICPGWVLTPLVQKQI-------------AQHDLLAEKQPS---LAFVTPEHLGELVLFLCSEAGSQVRGAAWNVDGGWL----

General information: TITO was launched using: RESULT: Template: 2Q2Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1346 -80676 -59.94 -341.85 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain C : 0.76 3D Compatibility (PKB) : -59.94 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_2Q2Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Q2Q-query.scw PDB file : Tito_Scwrl_2Q2Q.pdb: