Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNNTIETILNHRSIRSFTD-QLLTAEEIDTLVKSAQAASTSSYVQAYSIIGVSDPEKKRELSVLA-GNQPYVEKNGHFFVFCADLYRHQQ---LAEE---KGE---HI-----------SELLENTEMFMVSLIDAALAAQNMSIAAESMGLGICYIGGIRNELDKVTEVLQTPDH-VLPLFGLAVGHPANLSGKKPRLPKQAVYHENTYNVNTDDFRHTMNTYDKTISDYYRERTNGKREETWSDQILNFMKQKPRTYLNDYVKEKGFNKN 3GE6 Chain:A ((8-211)) -TDFMEIVKGRRSIRNYDTNVKISKEEMTQILEEATLAPSSVNMQPWRFLVIDSEEGKATLAPLAKFNQVQVETSSAVIAVFGDMKAIDQLENIYDTAVEKGLMPQEVRDRQVPAIQGMYENVPASALKDSILIDSGLVSMQLMLVARAHGYDTNPIGGY--EKDQIAEAFGMEKDRYVPVMLLSIGKAVDAGYPSVRLPINDIADW-----------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3GE6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 720 -9327 -12.95 -51.53 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -12.95 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.531

(partial model without unconserved sides chains): PDB file : Tito_3GE6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GE6-query.scw PDB file : Tito_Scwrl_3GE6.pdb: