Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLP--RGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE 3IG7 Chain:A ((7-288)) -----FQKVEKIGEGTYGVVYKARNKLTGEVVALKKI-----------VPSTAIREISLLKELN---HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF-----------TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP

General information: TITO was launched using: RESULT: Template: 3IG7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -2142 for 2037 contacts (-1.1/contact) + 2D Compatibility (PS) -26746 + (NN) -4421 + (LL) 1072 1D Compatibility (HY) 17600 + (ID) 750 Total energy: -15387.0 ( -7.55 by residue) QMean score : 0.073

(partial model without unconserved sides chains): PDB file : Tito_3IG7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IG7-query.scw PDB file : Tito_Scwrl_3IG7.pdb: