Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKWNPLIPFLLIAVLGIGLTFFLSVKGLDDSREIASGGESKSAEKKDANASPEEIYKANCIACHGENYEGVSGPSL-----KGVGDKKDVAEIKTKIEKGGNG------MPSGLVPADKLDDMAEWVSKIK 1YNR Chain:D ((10-79)) -----------------------------------------------------------CMACHDLKAKKV-GPAYADVAKKYAGRKDAVDYLAGKIKKGGSGVWGSVPMPPQNVTDAEAKQLAQWILSI-

General information: TITO was launched using: RESULT: Template: 1YNR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 149 9176 61.58 155.52 target 2D structure prediction score : 0.86 Monomeric hydrophicity matching model chain D : 0.63 3D Compatibility (PKB) : 61.58 2D Compatibility (Sec. Struct. Predict.) : 0.86 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.672

(partial model without unconserved sides chains): PDB file : Tito_1YNR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YNR-query.scw PDB file : Tito_Scwrl_1YNR.pdb: