Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRHALITAGSKGLGRKVTETLLAKGYSVTVNYRQDEEAVSRLKEACPDCLD-RLQFVKGDVTKKEDLLRIAEAALNRFGRIDFLINNAGPYIFERKKLADYTDDEWYGMLEGNLSAVFHLFKAVIPIMRKQQFGRIITYGFQGAAHAPGWL---HRSAFGAAKVGLASLTKTIAIEEAEFGITANMVCPGDIVGDMKEASIEEARMRIGKEKTPIGRSGTGEDIARIIAFLCEENSDLVTGTVIEATGGLNVINKNQTT 2ZTV Chain:B ((7-256)) ---AVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDGADLSKGEAVRGLVDNAVRQMGRIDILVNNAG--IQHTALIEDFPTEKWDAILALNLSAVFHGTAAALPHMKKQGFGRIINI-----ASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITANAICPGWVRTPLVEK---TAARELLSEKQPSLQFVTPEQLGGTAVFLASDAAAQITGTTVSVDGG----------

General information: TITO was launched using: RESULT: Template: 2ZTV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1238 -55455 -44.79 -239.03 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain B : 0.75 3D Compatibility (PKB) : -44.79 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.482

(partial model without unconserved sides chains): PDB file : Tito_2ZTV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ZTV-query.scw PDB file : Tito_Scwrl_2ZTV.pdb: