Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQRSLLFALLATLLLVGGARAETDPDYSMVLLTE-NFPPYNMAINGKNFAQ-EDNIDGIAVDIVREMFKRA-G--IKYSLTLRFPWDRIYKLALEKPGYGVFV-TARLAEREDKFKWVGPIGPDDWVLLAKGDSPITLGSLDEAKKYRIGAYKGDAIAEFLGK----NGFE-ADLAL-RDQENAQKLVKGQIDLWASGDPAGRYLAKQEGVTGLKTV-LRFNSDQLYLALNRETPDEVVQKLQAALDGMRKEGFVEDILNSYL 2V25 Chain:A ((33-258)) ---------------------SIKSKGQLIVGVKNDVPHYALLD------QATGEIKGFEVDVAKLLAKSILGDDKKIKLVA-VNAKTRGPLLDNGSVDAVIATFTITPERKRIYNFSEPYYQDAIGLLVLKEKK--YKSLADMKGANIGVAQAATTKKAIGEAAKKIGIDVKFSEFPDYPSIKAALDAKRVDAFSVDKSILLGYVDDK----SEILPDSFEPQSYGIVTKKDD-PAFAKYVDDFVKEHKN--EIDALAKKWG

General information: TITO was launched using: RESULT: Template: 2V25.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -111792 for 1713 contacts (-65.3/contact) + 2D Compatibility (PS) -22936 + (NN) -11523 + (LL) 2396 1D Compatibility (HY) -4000 + (ID) 1450 Total energy: -149305.0 ( -87.16 by residue) QMean score : 0.543

(partial model without unconserved sides chains): PDB file : Tito_2V25.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2V25-query.scw PDB file : Tito_Scwrl_2V25.pdb: