Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKIFAHRGASGQFPENTMLAFEKGIEAGADGIELDVQLTKDGRIVVIHDERLNRTTSLKGFVKDTAYDEVKTANAAAGHDQAYSDIKVPLLEDVLSWAVK-KDFLINIELKNSVIRYEGMEEKVL-EAVKRFNVEDRVILSTFNHDSLALCARLAPHIERAVLTSD-VLYQADRYIASIPASGYHPKINSPGVTDEVLKKMR-NGLIKVRPYTVNRPEDMKRLIEAGADGMFTDFPEKASALLKNE 1VD6 Chain:A ((7-223)) RPLRLGHRGAPLKAKENTLESFRLALEAGLDGVELDVWPTRDGVFAVRHDPDTP-----LGPVFQVDYADLKAQ-----------EPDLPRLEEVLALKEAFPQAVFNVELKSFPGLGEEAAR-RLAALLRG---REGVWVSSFDPLALLALRKAAPGLPLGFLMAEDHSAL---L-PCLGVEAVHPHH--ALVTEEAVAGWRKRG-LFVVAWTVNEEGEARRLLALGLDGLIGDRPEVLLPLG---

General information: TITO was launched using: RESULT: Template: 1VD6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1200 -4562 -3.80 -21.42 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -3.80 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_1VD6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VD6-query.scw PDB file : Tito_Scwrl_1VD6.pdb: