Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVNIIQDFIPVGANNRPGYAMTPLYITVHNTANTAVGADAAAHARYLKNPDTTTSWHFTVD--------DTEIYQHLPLNENGWHAGDGN----GSGNRASIGIEICENAD---------GDFAKATANA-QWLIKTLMAEHNISLANVVPHKYWS--GKECPRKLLDTWDSFKAGIGGGGSQTYVVKQGDTLTSIARAFGVTVAQLQEWNNIEDPNLIRVGQVLIVSAPSAAEKPELYPLPDGIIQLTTPYTSGEHVFQVQRALAALYFYPDKGAVNNGIDGVYGPKTADAVARFQSVNG-LTADGIYGPATKEKIAAQLS 3D2Y Chain:A ((26-255)) -------------------YPRIKVLVIHYTADDFDSS---LA-TLT---DKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGISAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKPENVVAHADIAPQRKDDPGPL-FPWQQLAQQGIGAWPD--------------------------------A----------QR------VN-FY-L------AGRAPHTPVDTASLLELLARYGYD-------VKPDM-TPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALL-

General information: TITO was launched using: RESULT: Template: 3D2Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1028 -68315 -66.45 -333.24 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -66.45 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.402

(partial model without unconserved sides chains): PDB file : Tito_3D2Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3D2Y-query.scw PDB file : Tito_Scwrl_3D2Y.pdb: