Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence METFKSILHEAQRIVVLTGAGMSTESGIPDFRSAGGIWTEDASRMEAMSLDYFLSYPRLFWPKFKELFQMKMSGSFEPNEGHLLLAELEKQGKQVDIFTQNIDGLHKKAGSRHVYELHGSIQTAACPACGARYDL---PHLLEREVPECTAAGNNGDICGTVLKTDVVLFGDAVMH--FDTLYEKLDQADLLLVIGTSLEVAPARFVPEDASLIPGMKKVIINLEP--TYCDSLFDMVIHQKIGEFARSLGMKK 1M2J Chain:A ((3-232)) -EKLLKTIAESKYLVALTGAGVSAESGIPTFRGKDGLWNRYRPE-ELANPQAFAKDPEKVWKWYA--WRMEKVFNAQPNKANQAFAELERLGVLKCLITQNVDDLHERAGSRNVIHLHGSLRVVRCTSCNNSFEVESAPKI--PPLPKC-------DKCGSLLRPGVVWFGEMLPPDVLDRAMREVERADVIIVAGTSAVVQPAASLP---LIVKQRGGAIIEINPDETPLTPIADYSLRGKAGEV--------

General information: TITO was launched using: RESULT: Template: 1M2J.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1179 -120602 -102.29 -540.82 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -102.29 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.442

(partial model without unconserved sides chains): PDB file : Tito_1M2J.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1M2J-query.scw PDB file : Tito_Scwrl_1M2J.pdb: