Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVNIIQDFIPVGANNR-PGYAMTPLYITVHNTANTAVGADAAAHARYLKNPDT-TTSWHFTVDDTEIYQHLPLNENGWHAGDGNGSGNRASIGIEICENADG-DFAKATANA-QWLIKTLMAEHNISLANVVPHKYWSGKECPRKLLD--TWDSFKAGIGGGGSQTYVVKQGDTLTSIARAFGVTVAQLQEWNNIEDPNLIRVGQVLIVSAPSAAEKPELYPLPDGIIQLTTPYTSGEHVFQVQRALAALYFYPDKGAVNNGIDGVYGPKTADAVARFQSVNGLTADGIYGPATKEKIAAQLS 1YB0 Chain:A ((1-155)) -MEIRKKLVVPSKYGTKCPYTMKPKYITVHNTYNDA-PAEN-EVNYMI--TNNNEVSFHVAVDDKQAIQGIPWERNAWACGDGNGPGNRESISVEICYSKSGGDRYYKAENNAVDVVRQLMSMYNIPIENVRTHQSWSGKYCPHRMLAEGRWGAFIQKVK-----------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1YB0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 815 -65103 -79.88 -436.93 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -79.88 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.485

(partial model without unconserved sides chains): PDB file : Tito_1YB0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YB0-query.scw PDB file : Tito_Scwrl_1YB0.pdb: