Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNK----LFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ----KAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN 2IZS Chain:A ((4-301)) ---------VLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLI--GRPGNKTQQVIHIIDFALAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW-IGKQLPTP----------------------------------

General information: TITO was launched using: RESULT: Template: 2IZS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -131942 for 2319 contacts (-56.9/contact) + 2D Compatibility (PS) -30931 + (NN) -10705 + (LL) 1512 1D Compatibility (HY) -29600 + (ID) 8000 Total energy: -209666.0 ( -90.41 by residue) QMean score : 0.497

(partial model without unconserved sides chains): PDB file : Tito_2IZS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IZS-query.scw PDB file : Tito_Scwrl_2IZS.pdb: