Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRF-LPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQGFN----LKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVL--QGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSF----PTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST 4BDK Chain:A ((14-284)) -----LRDEYIMSKTLG----GEVKLAFERKTCKKVAIKIISK---------ALNVETEIEILKKLNHPCIIKIKNFFDAEDYYI--VLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGET--SLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDE

General information: TITO was launched using: RESULT: Template: 4BDK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -127668 for 1752 contacts (-72.9/contact) + 2D Compatibility (PS) -26107 + (NN) -11428 + (LL) 1384 1D Compatibility (HY) -20400 + (ID) 4800 Total energy: -189019.0 ( -107.89 by residue) QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_4BDK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BDK-query.scw PDB file : Tito_Scwrl_4BDK.pdb: